INTENDED USE
Fagron TeloTest is intended to assist in making specific care
decisions regarding the prevention of
aging, especially in high yield diagnostic
settings, such as suspected cases of short
telomere syndromes.
Fagron TeloTest uses an automatized
qualitative algorithm that calculates
telomere length, infer biological age
based on telomere length, interpret
result and relevant patient’s anamnesis to
recommend the most appropriate formulas
and advice to delay the effect of ageing in
adult male and female population.
METHODOLOGY
Telomere length has been analyzed using DNA isolated from cells of the oral mucosa sample provided
DNA has been evaluated using the quantitative PCR technique ** (Absolute Human TelomerLength Quantification qPCR Assay Kit (AHTLQ); ScienceCell # 8918). Repeatability and reproducibility studies demonstrate validity greater than 99%.
The results indicate the average length of telomeres of all chromosomes from a comparison with a control sample with a known telomere length (reference sample).
The approximate biological age is estimated following statistical models endorsed by scientific publications, as well as by internal validations.